diff --git a/lib/ssluse.c b/lib/ssluse.c
index 7c4c9269aeeffd7891fe371ebc32a20769b8a521..92ae2e3e9ce890d3058b8a5ff5605b014eb17568 100644
--- a/lib/ssluse.c
+++ b/lib/ssluse.c
@@ -1501,6 +1501,10 @@ ossl_connect_step1(struct connectdata *conn,
   ctx_options |= SSL_OP_NO_TICKET;
 #endif
 
+#ifdef SSL_OP_NO_COMPRESSION
+  ctx_options |= SSL_OP_NO_COMPRESSION;
+#endif
+
 #ifdef SSL_OP_NETSCAPE_REUSE_CIPHER_CHANGE_BUG
   /* mitigate CVE-2010-4180 */
   ctx_options &= ~SSL_OP_NETSCAPE_REUSE_CIPHER_CHANGE_BUG;